The Center for Nuclear Receptors and Cell Signaling occupies 30,565 sq. ft. in the Science and Engineering Research Center (SERC), with open laboratory space designed to facilitate and enhance collaboration and cross-disciplinary research. The center’s state-of-the-art laboratories provide access to the latest research technologies for our research community. Center members have access to core facilities at the University of Houston and at the Houston Methodist Research Institute. Collaborations exist within UH, throughout the Texas Medical Center in Houston, and internationally.

Service Centers

Histology Core Service Center

The Histology Core Service Center provides histology consumables such as slides, chemicals, and tissue cassettes. The center also provides histology services including tissue processing, sectioning, H&E staining, immunohistochemistry, and documentation of stained slides. Histology Core Service Center Billing Rates

Service Facility Director: Dr. Sanghyuk Chung, Associate Professor

Histology

• Tissue processing machine
• Paraffin embedding station
• Microtome
• Cryostat

Imaging

• Nikon Ti2 inverted microscope
• IVIS Spectrum in vivo imaging system
• Zeiss PALM MicroBeam Laser Capture Microdisection system

Facilities

Mammalian Cell Imaging Facility

The FACS Aria II is a special order system including 5 lasers (488nm, 640nm, 561nm, 405nm and 355nm), making it possible to use 15 parameters and two- and four-way sorting into microtubes, 12x75mm, and 15mL tubes. An Automated Cell Deposition Unit (ACDU) allows for multiwall plate and slide sorting.

Clinical Samples and Tissue Analysis Facility

Our immunohistochemical staining lab includes several specialized microscopes; Olympus BX51 46hT flourescense, Olympus CX31 staining microscope, Olympus BX41 dual head microscope, Olympus IX with flourescense where we can visualize the expression pattern of any protein of interest.

Nucleic Acid Analysis Facility

A facility for analysis of nucleic acids e.g. miRNA, gene expression as well as quality control. (NanoDrop, Qubit, Applied Biosystems 7900HT Fast Real-time PCR System , 3x Applied Biosystems 7500 Fast Real-time PCR System, microarray lab)

Shared Facilities

• Transgenic Facility